![DLK-IN-1 Size:Contact sales@xcessbio.com for quotation Smiles: CCCCCC(O)/C=C/[C@@H]1C(C/C=C\CCCC(O)=O)C(O)CC1=O](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M21113_1635210778.gif?v=1635210779)
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Smiles: CCCCCC(O)/C=C/[C@@H]1C(C/C=C\CCCC(O)=O)C(O)CC1=O
InChiKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N
4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide
InChi: InChI=1S/C29H36F3N3O5/c1-28(2
with Kis of 8
DLK-IN-1 Size:Contact [email protected] for quotation Smiles: CCCCCC(O)/C=C/[C@@H]1C(C/C=C\CCCC(O)=O)C(O)CC1=ODLK IN 1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK IN 1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK IN 1 has activity in a model of Alzheimers Disease. Product information CAS Number: 1620574 24 4 Molecular Weight: 423. 43 Formula: C20H24F3N5O2 Chemical Name:
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